Evaluasi Potensi Hidrogel Ekstrak Daun Afrika (Vernonia Amygdalina) dalam Meningkatkan Penyembuhan Luka Perineum pada Kelinci (Oryctolagus Cuniculus)

Oktaviana Thresia Monika Barbara Adam; Suharyo Hadisaputro; Suryati Kumorowulan

doi:10.36990/hijp.v16i1.1157

Authors

Oktaviana Thresia Monika Barbara Adam Poltekkes Kemenkes Semarang, Indonesia
Suharyo Hadisaputro Poltekkes Kemenkes Semarang, Indonesia
Suryati Kumorowulan Balai Penelitian dan Pengembangan Kesehatan Magelang, Indonesia

DOI:

https://doi.org/10.36990/hijp.v16i1.1157

Keywords:

Hidrogel Daun Afrika, Luka Perineum

Abstract

Perineal rupture occurs in almost all vaginal deliveries experienced by women giving birth and will cause pain and discomfort, apart from that it will affect the mother's condition in providing lactation and daily care of her baby. Therefore, a good and effective perineal wound healing process is very important. One of the herbs that can be used to help speed up the healing process of perineal wounds is African Leaf (vernoniaa amygdalina), which contains substances that can speed up the wound healing process. In order to make the use of African leaves more visible, it is necessary to apply it to female rabbits (oryctolagus cuniculus) before being applied to the perineal wounds of postpartum mothers. The choice of hydrogel preparation is able to provide a cool feeling on the skin, thereby creating a comfortable feeling when applied to the target area and the preparation dries easily to form a film layer that is easily washed off with water. Design usedtrue experimentwith the research designrandomized post test with control group. The population of this study was 12 rabbits which were divided into 2 groups, namely group (I) treating clean dry wounds and group (II) treating wounds with 30% African leaf hydrogel 2 times a day for 7 days. Wound measurement uses a score scaleREEDA. Treatment was carried out for 7 days with the prevalence of the REEDA score assessed. Statistical test usingFriedmanAndMann Whitney.Timing test results healing of perineal wounds on the third to seventh day. Treatment for clean dry wounds heals longer than wounds treated with African leaf hydrogel. The results of the analysis for both groups showed a decrease in scaleREEDAwhich is significant on days 3.5 to 7, so it can be concluded that treating perineal wounds in rabbits by administering African leaf hydrogel can help speed up the healing process of perineal wounds.

References

Afrika, Daun, Vernonia Amygdalina, and D. E. L. Pada. n.d. “Uji Efek Penyembuhan Luka Sediaan Gel Ekstrak Etanol.” 184–87.

Atangwho, I. J., P. E. Ebong, E. U. Eyong, I. O. Williams, M. U. Eteng, and G. E. Egbung. 2009. “Comparative Chemical Composition of Leaves of Some Antidiabetic Medicinal Plants: Azadirachta Indica, Vernonia Amygdalina and Gongronema Latifolium.” African Journal of Biotechnology 8(18):4685–89. doi: 10.5897/AJB09.082.

Atikah, Nurul, Zelna Yuni Andryani. A, and Dewi Setiawati. 2020. “Manajemen Asuhan Kebidanan Masa Nifas Pada Ny ‘S’ Dengan Nyeri Luka Jahitan Perineum Pada Tanggal 24 Juli-03 September 2019 Di Rsud Syekh Yusuf Gowa Tahun 2019.” Jurnal Midwifery 2(2):78–84. doi: 10.24252/jm.v2i2a4.

Damarini, Susilo, Eliana Eliana, and Mariati Mariati. 2013. “Efektivitas Sirih Merah Dalam Perawatan Luka Perineum Di Bidan Praktik Mandiri.” Kesmas: National Public Health Journal 8(1):39. doi: 10.21109/kesmas.v8i1.340.

Ginting, Suventi Syafrina. 2020. “Perbandingan Efek Penyembuhan Luka Bakar Antara Gel Ekstrak Etanol Daun Afrika (Gymnanthemum Amygdalinum Del.)Dengan Gel Ekstrak Etanol Daun Kelapa Sawit ( Elaeis Guineensis Jacq.) Serta Kombinasinya Pada Kelinci TAHUN 2019.” Jurnal Penelitian Farmasi & Herbal 3(1):82–90. doi: 10.36656/jpfh.v3i1.327.

Kesehatan, Kementerian. 2016. Peraturan Menteri Kesehatan. Vol. 7.

M hakimi. 2010. Ilmu Kebidanan: Patologi & Fisiologi Persalinan. Yogyakarta: yayasan esentia medika.

Mustikasari, Susi Yanuari, Ignatius Hapsoro Wirandoko, and Ika Komala. 2020. “Efektifitas Ekstrak Daun Afrika (Vernonia Amygdalina) Terhadap Ketebalan Epitelisasi Pada Luka Insisi Mencit.” Jurnal Kedokteran & Kesehatan 6(3):12–18.

Nurhamida Fithri, & Simamora, L. 2022. “The Effect of Perineal Massage in Reducing Perineal Rupture during Labor.” Journal of Health (JoH) 9(1):9–16.

Pemiliana, P. D., Sarumpaet, I. H., & Ziliwu, D. S. 2019. “Faktor - Faktor Yang Berhubungan Dengan Ruptur Perineum Pada Persalinan Normal Di Klinik Niar Medan Tahun 2018.” Jurnal Kesehatan 170–182.

Putrianirma, Rizki, Nusdianto Triakoso, Maya Nurwartanti Yunita, Ira Sari Yudaniayanti, Iwan Sahrial Hamid, and Faisal Fikri. 2019. “Efektivitas Ekstrak Daun Afrika (Vernonia Amygdalina) Secara Topikal Untuk Reepitelisasi Penyembuhan Luka Insisi Pada Tikus Putih (Rattus Novergicus).” Jurnal Medik Veteriner 2(1):30. doi: 10.20473/jmv.vol2.iss1.2019.30-35.

Restiana, Elsa, Siti Khotimah, and Iit Fitrianingrum. 2016. “Uji Aktivitas Antibakteri Ekstrak Etil Asetat Pelepah Pisang Ambon (Musa Paradisiaca Linn .) Terhadap Propionibacterium Acnes.” Jurnal Cerebellum 2(2):422–33.

Rolyn Frisca Djamanmona. 2019. “Efektifitas Modern Dressing Dengan Hidrogel Nano Partikel Daun Afrika (Vernonia Amygdalina) Terhadap Jumlah Koloni Bakteri Dan Penyembuhan Luka Pada Pasien Luka Diabetik Grade Ii.”

Sabu N, Agustina. 2019. “Asuhan Kebidanan Berkelanjutan Pada Ny.B.S Puskesmas Bola Kabupaten Sikka Periode 30 April s/d 27 Juni 2019.”

Saranani, Muhaimin, Nurfantri Nurfantri, Akhmad Akhmad, and Budiono Budiono. 2023. “Efektivitas Pemberian Ekstrak Tanaman Komba-Komba (Lantana Camara) Terhadap Proses Penyembuhan Luka Pada Mencit Yang Diberi Luka Insisi: Penelitian Dengan Hewan Coba.” Health Information?: Jurnal Penelitian 15(3):e1113. doi: 10.36990/hijp.v15i3.1113.

Sukmarani, Siska. 2018. “Penerapan Pendidikan Kesehatan Perawatan Luka Perineum Pada Ibu Postpartum Dengan Pemenuhan Kebutuhan Belajar Di Puskesmas Godean I.” Jurnal Keperawatan 1(2):1–136.

Sukmawati, Sukmawati, Harira Hadi, and Aminah Aminah. 2017. “Potensi Senyawa Flavonoid Daun Afrika (Vernonia Amygdalina Del.) Asal Ternate sebagai antioksidan.” Jurnal ilmiah as-syifaa 9(2):195–200. Doi: 10.33096/jifa.v9i2.278.

Sulaiman, Akhmad Yusuf, Pudji Astuti, and Amandia Dewi Permana Shita. 2017. “Uji Antibakteri Ekstrak Daun Kersen (Muntingia Calabura L.) Terhadap Koloni Streptococcus Viridans.” Indonesian Journal for Health Sciences 1(2):1. doi: 10.24269/ijhs.v1i2.590.

Tottoli, Erika Maria, Rossella Dorati, Ida Genta, Enrica Chiesa, Silvia Pisani, and Bice Conti. 2020. “Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration.” Pharmaceutics 12(8):1–30.

Zulmi, Daini, Leri Septiani, and Suryani Soepardan. 2019. “The Effect of Sitting and Soaking Therapy with Binahong Leaf (Anredera Cordifolia) Decoction on Perineal Wound Healing.” Majalah Obstetri & Ginekologi 27(1):28. doi: 10.20473/mog.v1i12019.28-33.